Symptom pathogenesis during acute influenza: Interleukin-6 and Other cytokine responses

In experimental human influenza infection initiated by nasal inoculation, the magnitude of viral replication, fever, and symptoms correlate with nasopharyngeal lavage fluid levels of various cytokines. Our aim was to assess these relationships in patients with naturally occurring acute influenza. Pa...

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Veröffentlicht in:	Journal of medical virology 2001-07, Vol.64 (3), p.262-268
Hauptverfasser:	Kaiser, Laurent, Fritz, R. Scott, Straus, Stephen E., Gubareva, Larisa, Hayden, Frederick G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences cytokines Cytokines - analysis Cytokines - blood Enzyme-Linked Immunosorbent Assay Fever - complications Fundamental and applied biological sciences. Psychology Humans influenza Influenza A virus Influenza virus influenza virus A Influenza, Human - diagnosis Influenza, Human - immunology Influenza, Human - virology Interferon-alpha - analysis Interferon-alpha - blood Interferon-gamma - analysis Interferon-gamma - blood interferon-α interferon-γ interleukin-10 Interleukin-10 - analysis Interleukin-10 - blood interleukin-6 Interleukin-6 - analysis Interleukin-6 - blood interleukin-8 Microbiology Nasal Lavage Fluid - immunology Nasal Lavage Fluid - virology oseltamivir Reverse Transcriptase Polymerase Chain Reaction RNA, Viral - analysis RNA, Viral - blood Statistics as Topic Tumor Necrosis Factor-alpha - analysis tumor necrosis factor-α Viremia - virology Virus Replication
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