Some reactions with ketene dithioacetals part I: synthesis of antimicrobial pyrazol

Pyrazolo[1,5-a]pyrimidines were synthesized via the reaction of ketene dithioacetals and 5-aminopyrazoles. The antibacterial and antifungal activities of some selected compounds are also reported.

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Bibliographische Detailangaben
Veröffentlicht in:	Farmaco (Società chimica italiana : 1989) 2001-04, Vol.56 (4), p.277-283
Hauptverfasser:	Zaharan, M A, El-Sharief, A M, El-Gaby, M S, Ammar, Y A, El-Said, U H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetals - chemistry Anti-Bacterial Agents Anti-Infective Agents - chemical synthesis Anti-Infective Agents - pharmacology Antifungal Agents - chemical synthesis Antifungal Agents - pharmacology Bacteria - drug effects Fungi - drug effects Indicators and Reagents Magnetic Resonance Spectroscopy Microbial Sensitivity Tests Pyrazoles - chemical synthesis Pyrazoles - pharmacology Pyrimidines - chemical synthesis Pyrimidines - pharmacology Spectrophotometry, Infrared
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Beschreibung
Zusammenfassung:	Pyrazolo[1,5-a]pyrimidines were synthesized via the reaction of ketene dithioacetals and 5-aminopyrazoles. The antibacterial and antifungal activities of some selected compounds are also reported.
ISSN:	0014-827X