Chemical Constituents from Drypetes littoralis

Chemical investigation of Drypetes littoralis yielded three new tricyclic diterpenes, drypetenones A, B, and C (1--3), and one new xanthone (4). Spectral analyses and chemical correlations established the structures as 10S-12-hydroxy-11-methoxy-13-methylpodocarpa-1,5,8,11,13-pentaene-3,7-dione, (1),...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2001-06, Vol.64 (6), p.707-709
Hauptverfasser:	LIN, Mei-Tsu, CHEN, Lih-Chun, CHEN, Chien-Kuang, CHEN LIU, Karin C. S., LEE, Shoei-Sheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Biological and medical sciences Diterpenes - chemistry Diterpenes - isolation & purification Euphorbiaceae - chemistry General pharmacology Mass Spectrometry Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - chemistry Plants, Medicinal - chemistry Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Taiwan
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Zusammenfassung:	Chemical investigation of Drypetes littoralis yielded three new tricyclic diterpenes, drypetenones A, B, and C (1--3), and one new xanthone (4). Spectral analyses and chemical correlations established the structures as 10S-12-hydroxy-11-methoxy-13-methylpodocarpa-1,5,8,11,13-pentaene-3,7-dione, (1), 10S-12-hydroxy-11-methoxy-13-methylpodocarpa-5,8,11,13-tetraene-3,7-dione (2), 10S-12-hydroxy-6,11-dimethoxy-13-methylpodocarpa-1,5,8,11,13-pentaene-3,7-dione (3), and 1-hydroxy-7-hydroxymethyl-6-methoxyxanthone (4). Complete (13)C NMR assignment of boehmenan D (5) is also made.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np0005964