Deep Vein Thrombosis Prophylaxis in Hip Fractures: A Comparison of the Arteriovenous Impulse System and Aspirin
BACKGROUND:A prospective, randomized controlled trial was used to compare the efficacy of the arteriovenous (AV) impulse system and aspirin in reducing venous thrombosis after fracture to the femoral neck. METHODS:A total of 143 patients underwent hemiarthroplasty, after which 70 patients were treat...
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| Veröffentlicht in: | The journal of trauma 2000-02, Vol.48 (2), p.268-372 |
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| container_title | The journal of trauma |
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| creator | Kennedy, John G. Soffe, Karen E. Rogers, Blake W. Kumar, Sunil Griffen, Denis R. Dallo Vedova, Pietro A. Sullivan, Raymond J. Sheehan, Lester J. |
| description | BACKGROUND:A prospective, randomized controlled trial was used to compare the efficacy of the arteriovenous (AV) impulse system and aspirin in reducing venous thrombosis after fracture to the femoral neck.
METHODS:A total of 143 patients underwent hemiarthroplasty, after which 70 patients were treated with the AV pump and a second group of 73 patients were commenced on 325 mg of aspirin. Duplex ultrasound was used to assess both proximal and distal venous thrombi on days 7 to 10. Calf and thigh circumferences were also measured.
RESULTS:Thrombi developed in seven of the patients treated with aspirin and in four patients treated with the AV pump. No statistically significant difference could be established (p = 0.109). There was a significant reduction in both calf (p = 0.003) and thigh (p = 0.002) swelling in the group treated with the AV pump. Neither treatment group was a significant predictor of a poorer outcome by using logistical regression analysis (p = 0.258).
CONCLUSIONS:Both aspirin and the AV pump are effective in reducing thromboembolic events after hemiarthroplasty of the hip. |
| doi_str_mv | 10.1097/00005373-200002000-00012 |
| format | Article |
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METHODS:A total of 143 patients underwent hemiarthroplasty, after which 70 patients were treated with the AV pump and a second group of 73 patients were commenced on 325 mg of aspirin. Duplex ultrasound was used to assess both proximal and distal venous thrombi on days 7 to 10. Calf and thigh circumferences were also measured.
RESULTS:Thrombi developed in seven of the patients treated with aspirin and in four patients treated with the AV pump. No statistically significant difference could be established (p = 0.109). There was a significant reduction in both calf (p = 0.003) and thigh (p = 0.002) swelling in the group treated with the AV pump. Neither treatment group was a significant predictor of a poorer outcome by using logistical regression analysis (p = 0.258).
CONCLUSIONS:Both aspirin and the AV pump are effective in reducing thromboembolic events after hemiarthroplasty of the hip.</description><identifier>ISSN: 0022-5282</identifier><identifier>EISSN: 1529-8809</identifier><identifier>DOI: 10.1097/00005373-200002000-00012</identifier><identifier>PMID: 10697085</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins, Inc</publisher><subject>Aged ; Aspirin - therapeutic use ; Cardiology - instrumentation ; Female ; Femoral Neck Fractures - complications ; Humans ; Leg - blood supply ; Male ; Platelet Aggregation Inhibitors - therapeutic use ; Prospective Studies ; Venous Thrombosis - etiology ; Venous Thrombosis - prevention & control</subject><ispartof>The journal of trauma, 2000-02, Vol.48 (2), p.268-372</ispartof><rights>2000 Lippincott Williams & Wilkins, Inc.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3562-5f00d02cdf09831365e7f984a276b5c4cd1b9fc5eccf08ac4f09b4ac2010e88b3</citedby><cites>FETCH-LOGICAL-c3562-5f00d02cdf09831365e7f984a276b5c4cd1b9fc5eccf08ac4f09b4ac2010e88b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10697085$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kennedy, John G.</creatorcontrib><creatorcontrib>Soffe, Karen E.</creatorcontrib><creatorcontrib>Rogers, Blake W.</creatorcontrib><creatorcontrib>Kumar, Sunil</creatorcontrib><creatorcontrib>Griffen, Denis R.</creatorcontrib><creatorcontrib>Dallo Vedova, Pietro A.</creatorcontrib><creatorcontrib>Sullivan, Raymond J.</creatorcontrib><creatorcontrib>Sheehan, Lester J.</creatorcontrib><title>Deep Vein Thrombosis Prophylaxis in Hip Fractures: A Comparison of the Arteriovenous Impulse System and Aspirin</title><title>The journal of trauma</title><addtitle>J Trauma</addtitle><description>BACKGROUND:A prospective, randomized controlled trial was used to compare the efficacy of the arteriovenous (AV) impulse system and aspirin in reducing venous thrombosis after fracture to the femoral neck.
METHODS:A total of 143 patients underwent hemiarthroplasty, after which 70 patients were treated with the AV pump and a second group of 73 patients were commenced on 325 mg of aspirin. Duplex ultrasound was used to assess both proximal and distal venous thrombi on days 7 to 10. Calf and thigh circumferences were also measured.
RESULTS:Thrombi developed in seven of the patients treated with aspirin and in four patients treated with the AV pump. No statistically significant difference could be established (p = 0.109). There was a significant reduction in both calf (p = 0.003) and thigh (p = 0.002) swelling in the group treated with the AV pump. Neither treatment group was a significant predictor of a poorer outcome by using logistical regression analysis (p = 0.258).
CONCLUSIONS:Both aspirin and the AV pump are effective in reducing thromboembolic events after hemiarthroplasty of the hip.</description><subject>Aged</subject><subject>Aspirin - therapeutic use</subject><subject>Cardiology - instrumentation</subject><subject>Female</subject><subject>Femoral Neck Fractures - complications</subject><subject>Humans</subject><subject>Leg - blood supply</subject><subject>Male</subject><subject>Platelet Aggregation Inhibitors - therapeutic use</subject><subject>Prospective Studies</subject><subject>Venous Thrombosis - etiology</subject><subject>Venous Thrombosis - prevention & control</subject><issn>0022-5282</issn><issn>1529-8809</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1PxCAQQInR6Lr6Fwwnb1Wg7Ra8bdaPNTHRxNUroXSaom2p0Lruv5e1arxIAkwyb4bJAyFMyRklIjsnYaVxFkdsG22PKGzKdtCEpkxEnBOxiyYhxaKUcXaADr1_CUiSxHwfHVAyExnh6QTZS4AOP4Np8apytsmtNx4_ONtVm1p9hDhklqbD107pfnDgL_AcL2zTKWe8bbEtcV8BnrsenLHv0NrB49umG2oP-HHje2iwags8951xpj1Ce6UKqePve4qerq9Wi2V0d39zu5jfRTpOZ2HokpCCMF2URPCYxrMUslLwRLFslqc60QXNRalT0LokXOkkcHmiNCOUAOd5PEWnY9_O2bcBfC8b4zXUtWohTCgzIoIKwQLIR1A7672DUnbONMptJCVyK1v-yJa_suWX7FB68v3GkDdQ_Ckc7QYgGYG1rYMe_1oPa3CyAlX3lfzvE-NPk3qKlA</recordid><startdate>200002</startdate><enddate>200002</enddate><creator>Kennedy, John G.</creator><creator>Soffe, Karen E.</creator><creator>Rogers, Blake W.</creator><creator>Kumar, Sunil</creator><creator>Griffen, Denis R.</creator><creator>Dallo Vedova, Pietro A.</creator><creator>Sullivan, Raymond J.</creator><creator>Sheehan, Lester J.</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200002</creationdate><title>Deep Vein Thrombosis Prophylaxis in Hip Fractures: A Comparison of the Arteriovenous Impulse System and Aspirin</title><author>Kennedy, John G. ; Soffe, Karen E. ; Rogers, Blake W. ; Kumar, Sunil ; Griffen, Denis R. ; Dallo Vedova, Pietro A. ; Sullivan, Raymond J. ; Sheehan, Lester J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3562-5f00d02cdf09831365e7f984a276b5c4cd1b9fc5eccf08ac4f09b4ac2010e88b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Aged</topic><topic>Aspirin - therapeutic use</topic><topic>Cardiology - instrumentation</topic><topic>Female</topic><topic>Femoral Neck Fractures - complications</topic><topic>Humans</topic><topic>Leg - blood supply</topic><topic>Male</topic><topic>Platelet Aggregation Inhibitors - therapeutic use</topic><topic>Prospective Studies</topic><topic>Venous Thrombosis - etiology</topic><topic>Venous Thrombosis - prevention & control</topic><toplevel>online_resources</toplevel><creatorcontrib>Kennedy, John G.</creatorcontrib><creatorcontrib>Soffe, Karen E.</creatorcontrib><creatorcontrib>Rogers, Blake W.</creatorcontrib><creatorcontrib>Kumar, Sunil</creatorcontrib><creatorcontrib>Griffen, Denis R.</creatorcontrib><creatorcontrib>Dallo Vedova, Pietro A.</creatorcontrib><creatorcontrib>Sullivan, Raymond J.</creatorcontrib><creatorcontrib>Sheehan, Lester J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The journal of trauma</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kennedy, John G.</au><au>Soffe, Karen E.</au><au>Rogers, Blake W.</au><au>Kumar, Sunil</au><au>Griffen, Denis R.</au><au>Dallo Vedova, Pietro A.</au><au>Sullivan, Raymond J.</au><au>Sheehan, Lester J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Deep Vein Thrombosis Prophylaxis in Hip Fractures: A Comparison of the Arteriovenous Impulse System and Aspirin</atitle><jtitle>The journal of trauma</jtitle><addtitle>J Trauma</addtitle><date>2000-02</date><risdate>2000</risdate><volume>48</volume><issue>2</issue><spage>268</spage><epage>372</epage><pages>268-372</pages><issn>0022-5282</issn><eissn>1529-8809</eissn><abstract>BACKGROUND:A prospective, randomized controlled trial was used to compare the efficacy of the arteriovenous (AV) impulse system and aspirin in reducing venous thrombosis after fracture to the femoral neck.
METHODS:A total of 143 patients underwent hemiarthroplasty, after which 70 patients were treated with the AV pump and a second group of 73 patients were commenced on 325 mg of aspirin. Duplex ultrasound was used to assess both proximal and distal venous thrombi on days 7 to 10. Calf and thigh circumferences were also measured.
RESULTS:Thrombi developed in seven of the patients treated with aspirin and in four patients treated with the AV pump. No statistically significant difference could be established (p = 0.109). There was a significant reduction in both calf (p = 0.003) and thigh (p = 0.002) swelling in the group treated with the AV pump. Neither treatment group was a significant predictor of a poorer outcome by using logistical regression analysis (p = 0.258).
CONCLUSIONS:Both aspirin and the AV pump are effective in reducing thromboembolic events after hemiarthroplasty of the hip.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>10697085</pmid><doi>10.1097/00005373-200002000-00012</doi><tpages>105</tpages></addata></record> |
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| identifier | ISSN: 0022-5282 |
| ispartof | The journal of trauma, 2000-02, Vol.48 (2), p.268-372 |
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| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Aged Aspirin - therapeutic use Cardiology - instrumentation Female Femoral Neck Fractures - complications Humans Leg - blood supply Male Platelet Aggregation Inhibitors - therapeutic use Prospective Studies Venous Thrombosis - etiology Venous Thrombosis - prevention & control |
| title | Deep Vein Thrombosis Prophylaxis in Hip Fractures: A Comparison of the Arteriovenous Impulse System and Aspirin |
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