Ultraviolet B-Induced Suppression of Immune Responses in Interleukin-4–/– Mice: Relationship to Dermal Mast Cells

Ultraviolet B radiation is immunosuppressive by multiple mechanisms. In interleukin-4–/– mice, ultraviolet B radiation was not able to suppress delayed-type hypersensitivity or contact hypersensitivity responses when the sensitizing antigen was applied to nonirradiated sites. In contrast, ultraviole...

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Veröffentlicht in:	Journal of investigative dermatology 2000-03, Vol.114 (3), p.508-513
Hauptverfasser:	Hart, Prue H., Grimbaldeston, Michele A., Jaksic, Aleksandra, Swift, Georgina J., Hosszu, Emma K., Finlay-Jones, John J., Tan, Joy E., Halliday, Gary M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibody Formation - radiation effects Biological and medical sciences Biological effects of radiation c-kit Cell Count Cell Degranulation cis-urocanic acid dermal mast cells Dermatitis, Contact - etiology Fundamental and applied biological sciences. Psychology histamine Hypersensitivity, Delayed - pathology Interleukin-10 - blood interleukin-4 Interleukin-4 - analysis Mast Cells - cytology Mast Cells - immunology Mast Cells - radiation effects Mice Mice, Inbred C57BL Non ionizing radiations. Hertzian waves. Biooptics Picryl Chloride - immunology serum interleukin-10 Skin - cytology Skin - radiation effects Spleen - cytology Tissues, organs and organisms biophysics ultraviolet B Ultraviolet Rays
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