Limiting dilution analysis: from frequencies to cellular interactions

Molecular biology techniques have provided the means to pursue the precise definition of molecular components in a single cell type and its clonal progeny. However, to study the workings of the individual components of the immune system as well as the system itself, additional tools and supplementar...

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Veröffentlicht in:	Immunology today (Amsterdam. Regular ed.) 2000, Vol.21 (1), p.15-18
Hauptverfasser:	Dozmorov, Igor, Eisenbraun, Michael D, Lefkovits, Ivan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Communication - immunology Clone Cells In vitro response limiting dilution analysis Lymphocyte Count - methods Mixed-lymphocyte reaction Non-linear model Single-hit kinetics T-Lymphocyte Subsets - cytology T-Lymphocyte Subsets - immunology Virgin and memory cells Zigzag phenomenon
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Beschreibung
Zusammenfassung:	Molecular biology techniques have provided the means to pursue the precise definition of molecular components in a single cell type and its clonal progeny. However, to study the workings of the individual components of the immune system as well as the system itself, additional tools and supplementary approaches are required.
ISSN:	0167-5699
DOI:	10.1016/S0167-5699(99)01561-3