An Outbreak of Streptococcus pneumoniae Serotype 1 in a Closed Community in Southern Israel

An outbreak of Streptococcus pneumoniae serotype 1 occurred in a closed community that was characterized by poverty and crowding. Vaccine was administered to individuals aged >2 years; no new cases occurred among vaccine recipients. Six weeks after vaccination, carriage of serotype 1, but not of...

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Veröffentlicht in:Clinical infectious diseases 2000-02, Vol.30 (2), p.319-321
Hauptverfasser: Dagan, Ron, Gradstein, Serge, Belmaker, Ilana, Porat, Nurith, Siton, Yaffa, Weber, Gabriel, Janco, Jacob, Yagupsky, Pablo
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Sprache:eng
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Zusammenfassung:An outbreak of Streptococcus pneumoniae serotype 1 occurred in a closed community that was characterized by poverty and crowding. Vaccine was administered to individuals aged >2 years; no new cases occurred among vaccine recipients. Six weeks after vaccination, carriage of serotype 1, but not of other serotypes, decreased 8.8-fold. This suggests that the reduction in serotype 1 carriage reflects the natural course of the outbreak rather than a vaccine effect. Polysaccharide vaccine may be helpful in terminating pneumococcal outbreaks but may not affect pneumococcal carriage.
ISSN:1058-4838
1537-6591
DOI:10.1086/313645