A simple method for constructing microinjectrodes for reversible inactivation in behaving monkeys

A method for constructing a simple, durable injection-microelectrode (injectrode) is described. The injectrode can record neuronal activity, stimulate neuronal tissues, or inject substances locally through its tip. The injectrode is lightweight and is easy to construct from commercially available pa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuroscience methods 2001-05, Vol.107 (1), p.81-85
Hauptverfasser:	Chen, Longtang L, Goffart, Laurent, Sparks, David L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Behavior, Animal - physiology Biological and medical sciences Brain - drug effects Brain - physiology Brain - surgery Cortex Drug Delivery Systems - instrumentation Drug Delivery Systems - methods Dura Mater - surgery Electrophysiology - instrumentation Electrophysiology - methods Fundamental and applied biological sciences. Psychology General aspects. Models. Methods Haplorhini - anatomy & histology Haplorhini - physiology Haplorhini - surgery Head-unrestrained Injection-microelectrode Microelectrodes - standards Monkey Neurons - cytology Neurons - drug effects Neurons - physiology Reversible inactivation Stereotaxic Techniques - instrumentation Syringes - standards Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A method for constructing a simple, durable injection-microelectrode (injectrode) is described. The injectrode can record neuronal activity, stimulate neuronal tissues, or inject substances locally through its tip. The injectrode is lightweight and is easy to construct from commercially available parts, and it can be used repeatedly for multiple recordings and injections. Since dura penetration can damage fragile electrode tips, a reliable method to pass the injectrode through an intact dura matter is described.
ISSN:	0165-0270 1872-678X
DOI:	10.1016/S0165-0270(01)00354-5