The hypoglycemic activity of Zygophyllum gaetulum extracts in alloxan-induced hyperglycemic rats

The aqueous infusion of the aerial parts of Zygophyllum gaetulum Emb. and Maire was tested orally (1 g/kg body weight) for hypoglycemic activity in alloxan-induced diabetic rats. The infusion was partitioned between water and butanol to yield a butanol soluble fraction (B), and an aqueous fraction (...

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Veröffentlicht in:	Journal of ethnopharmacology 2000, Vol.69 (1), p.17-20
Hauptverfasser:	Jaouhari, J.T, Lazrek, H.B, Jana, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alloxan-induced diabetic rat Animals Biological and medical sciences Blood Glucose - drug effects Blood Glucose - metabolism Diabetes Mellitus, Experimental - drug therapy General pharmacology Hypoglycemic activity Hypoglycemic Agents - pharmacology Male Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology Rats Rats, Wistar Solubility Zygophyllum gaetulum
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Zusammenfassung:	The aqueous infusion of the aerial parts of Zygophyllum gaetulum Emb. and Maire was tested orally (1 g/kg body weight) for hypoglycemic activity in alloxan-induced diabetic rats. The infusion was partitioned between water and butanol to yield a butanol soluble fraction (B), and an aqueous fraction (W) which on reduction in volume gave a precipitate (WP) and supernatant (WS). Fractions (B) and (WP) caused significant reduction in blood glucose concentration, while the ingestion of (WS) produced no significant reduction in blood glucose level.
ISSN:	0378-8741 1872-7573
DOI:	10.1016/S0378-8741(99)00064-1