Rare polymorphisms in the promoter regions of the human interleukin-12 p35 and interleukin-12 p40 subunit genes

Rare polymorphisms in the promoter regions of the human interleukin-12 p35 and interleukin-12 p40 subunit genes

We have described two rare, single‐nucleotide polymorphisms within the promoter regions of the IL‐12 p35 and p40 subunit genes. Transitions C to T at position −916 from the transcription start of the IL‐12 p35 gene and G to T at position −1287 in the IL‐12 p40 gene were observed.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:European journal of immunogenetics 2000-02, Vol.27 (1), p.35-36
Hauptverfasser: Pravica, Vera, Brogan, Iain J., Hutchinson, Ian V.
Format: Artikel
Sprache:eng
Schlagworte:
Base Sequence
Conserved Sequence
Genetic Variation
Humans
Interleukin-12 - genetics
Molecular Sequence Data
p35 protein
p40 protein
Polymorphism, Genetic
Polymorphism, Single-Stranded Conformational
Promoter Regions, Genetic
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 36
container_issue 1
container_start_page 35
container_title European journal of immunogenetics
container_volume 27
creator Pravica, Vera
Brogan, Iain J.
Hutchinson, Ian V.
description We have described two rare, single‐nucleotide polymorphisms within the promoter regions of the IL‐12 p35 and p40 subunit genes. Transitions C to T at position −916 from the transcription start of the IL‐12 p35 gene and G to T at position −1287 in the IL‐12 p40 gene were observed.
doi_str_mv 10.1046/j.1365-2370.2000.00190.x
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70893077</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>70893077</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4990-cdd3592f5616164f4c600c3d9e9b7d26d59da2f25df0db1b1845f9307464d4d63</originalsourceid><addsrcrecordid>eNqNkUtv1DAUhS0EokPhLyCv2CVcv8cSG1RBZ6ryEALBzkpip-NpEg92Imb-PU5TVUgsQF7Yuvc7x7r3IIQJlAS4fL0vCZOioExBSQGgBCAayuMjtHpoPEYr0BIKxSmcoWcp7TPEiJZP0RkBKcia6xUKX6ro8CF0pz7Ew86nPmE_4HGXizH0YXQRR3fjw5BwaO_qu6mvhgzlVuemWz8UhOIDE7ga7F9lDjhN9TT4Ed-4waXn6Elbdcm9uL_P0bf3775ebIrrT5fbi7fXRcO1hqKxlglNWyFJPrzljQRomNVO18pSaYW2FW2psC3YmtR5GNFqBopLbrmV7By9WnzzFD8nl0bT-9S4rqsGF6ZkFKxnXP0TJEoAKEkzuF7AJoaUomvNIfq-iidDwMypmL2Zl2_m5Zs5FXOXijlm6cv7P6a6d_YP4RJDBt4swC_fudN_G5vt1TY_srxY5D6N7vggr-KtkYopYb5_vDRXPzb684eNzl6_AfCLqXY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>17500762</pqid></control><display><type>article</type><title>Rare polymorphisms in the promoter regions of the human interleukin-12 p35 and interleukin-12 p40 subunit genes</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Pravica, Vera ; Brogan, Iain J. ; Hutchinson, Ian V.</creator><creatorcontrib>Pravica, Vera ; Brogan, Iain J. ; Hutchinson, Ian V.</creatorcontrib><description>We have described two rare, single‐nucleotide polymorphisms within the promoter regions of the IL‐12 p35 and p40 subunit genes. Transitions C to T at position −916 from the transcription start of the IL‐12 p35 gene and G to T at position −1287 in the IL‐12 p40 gene were observed.</description><identifier>ISSN: 0960-7420</identifier><identifier>EISSN: 1365-2370</identifier><identifier>DOI: 10.1046/j.1365-2370.2000.00190.x</identifier><identifier>PMID: 10651849</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>Base Sequence ; Conserved Sequence ; Genetic Variation ; Humans ; Interleukin-12 - genetics ; Molecular Sequence Data ; p35 protein ; p40 protein ; Polymorphism, Genetic ; Polymorphism, Single-Stranded Conformational ; Promoter Regions, Genetic</subject><ispartof>European journal of immunogenetics, 2000-02, Vol.27 (1), p.35-36</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4990-cdd3592f5616164f4c600c3d9e9b7d26d59da2f25df0db1b1845f9307464d4d63</citedby><cites>FETCH-LOGICAL-c4990-cdd3592f5616164f4c600c3d9e9b7d26d59da2f25df0db1b1845f9307464d4d63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1046%2Fj.1365-2370.2000.00190.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1046%2Fj.1365-2370.2000.00190.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10651849$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pravica, Vera</creatorcontrib><creatorcontrib>Brogan, Iain J.</creatorcontrib><creatorcontrib>Hutchinson, Ian V.</creatorcontrib><title>Rare polymorphisms in the promoter regions of the human interleukin-12 p35 and interleukin-12 p40 subunit genes</title><title>European journal of immunogenetics</title><addtitle>Eur J Immunogenet</addtitle><description>We have described two rare, single‐nucleotide polymorphisms within the promoter regions of the IL‐12 p35 and p40 subunit genes. Transitions C to T at position −916 from the transcription start of the IL‐12 p35 gene and G to T at position −1287 in the IL‐12 p40 gene were observed.</description><subject>Base Sequence</subject><subject>Conserved Sequence</subject><subject>Genetic Variation</subject><subject>Humans</subject><subject>Interleukin-12 - genetics</subject><subject>Molecular Sequence Data</subject><subject>p35 protein</subject><subject>p40 protein</subject><subject>Polymorphism, Genetic</subject><subject>Polymorphism, Single-Stranded Conformational</subject><subject>Promoter Regions, Genetic</subject><issn>0960-7420</issn><issn>1365-2370</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUtv1DAUhS0EokPhLyCv2CVcv8cSG1RBZ6ryEALBzkpip-NpEg92Imb-PU5TVUgsQF7Yuvc7x7r3IIQJlAS4fL0vCZOioExBSQGgBCAayuMjtHpoPEYr0BIKxSmcoWcp7TPEiJZP0RkBKcia6xUKX6ro8CF0pz7Ew86nPmE_4HGXizH0YXQRR3fjw5BwaO_qu6mvhgzlVuemWz8UhOIDE7ga7F9lDjhN9TT4Ed-4waXn6Elbdcm9uL_P0bf3775ebIrrT5fbi7fXRcO1hqKxlglNWyFJPrzljQRomNVO18pSaYW2FW2psC3YmtR5GNFqBopLbrmV7By9WnzzFD8nl0bT-9S4rqsGF6ZkFKxnXP0TJEoAKEkzuF7AJoaUomvNIfq-iidDwMypmL2Zl2_m5Zs5FXOXijlm6cv7P6a6d_YP4RJDBt4swC_fudN_G5vt1TY_srxY5D6N7vggr-KtkYopYb5_vDRXPzb684eNzl6_AfCLqXY</recordid><startdate>200002</startdate><enddate>200002</enddate><creator>Pravica, Vera</creator><creator>Brogan, Iain J.</creator><creator>Hutchinson, Ian V.</creator><general>Blackwell Science Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>200002</creationdate><title>Rare polymorphisms in the promoter regions of the human interleukin-12 p35 and interleukin-12 p40 subunit genes</title><author>Pravica, Vera ; Brogan, Iain J. ; Hutchinson, Ian V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4990-cdd3592f5616164f4c600c3d9e9b7d26d59da2f25df0db1b1845f9307464d4d63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Base Sequence</topic><topic>Conserved Sequence</topic><topic>Genetic Variation</topic><topic>Humans</topic><topic>Interleukin-12 - genetics</topic><topic>Molecular Sequence Data</topic><topic>p35 protein</topic><topic>p40 protein</topic><topic>Polymorphism, Genetic</topic><topic>Polymorphism, Single-Stranded Conformational</topic><topic>Promoter Regions, Genetic</topic><toplevel>online_resources</toplevel><creatorcontrib>Pravica, Vera</creatorcontrib><creatorcontrib>Brogan, Iain J.</creatorcontrib><creatorcontrib>Hutchinson, Ian V.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of immunogenetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pravica, Vera</au><au>Brogan, Iain J.</au><au>Hutchinson, Ian V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rare polymorphisms in the promoter regions of the human interleukin-12 p35 and interleukin-12 p40 subunit genes</atitle><jtitle>European journal of immunogenetics</jtitle><addtitle>Eur J Immunogenet</addtitle><date>2000-02</date><risdate>2000</risdate><volume>27</volume><issue>1</issue><spage>35</spage><epage>36</epage><pages>35-36</pages><issn>0960-7420</issn><eissn>1365-2370</eissn><abstract>We have described two rare, single‐nucleotide polymorphisms within the promoter regions of the IL‐12 p35 and p40 subunit genes. Transitions C to T at position −916 from the transcription start of the IL‐12 p35 gene and G to T at position −1287 in the IL‐12 p40 gene were observed.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>10651849</pmid><doi>10.1046/j.1365-2370.2000.00190.x</doi><tpages>2</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0960-7420
ispartof European journal of immunogenetics, 2000-02, Vol.27 (1), p.35-36
issn 0960-7420
1365-2370
language eng
recordid cdi_proquest_miscellaneous_70893077
source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Base Sequence
Conserved Sequence
Genetic Variation
Humans
Interleukin-12 - genetics
Molecular Sequence Data
p35 protein
p40 protein
Polymorphism, Genetic
Polymorphism, Single-Stranded Conformational
Promoter Regions, Genetic
title Rare polymorphisms in the promoter regions of the human interleukin-12 p35 and interleukin-12 p40 subunit genes
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-15T00%3A07%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Rare%20polymorphisms%20in%20the%20promoter%20regions%20of%20the%20human%20interleukin-12%20p35%20and%20interleukin-12%20p40%20subunit%20genes&rft.jtitle=European%20journal%20of%20immunogenetics&rft.au=Pravica,%20Vera&rft.date=2000-02&rft.volume=27&rft.issue=1&rft.spage=35&rft.epage=36&rft.pages=35-36&rft.issn=0960-7420&rft.eissn=1365-2370&rft_id=info:doi/10.1046/j.1365-2370.2000.00190.x&rft_dat=%3Cproquest_cross%3E70893077%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=17500762&rft_id=info:pmid/10651849&rfr_iscdi=true