Effect of Prostaglandin A1 Arsenite and Aspirin on Stress Proteins Response in Mosquito Cells

Effect of Prostaglandin A1 Arsenite and Aspirin on Stress Proteins Response in Mosquito Cells

The stress response of eukaryotic cells is characterized by changes in the metabolism of responding cells, most notably by increased synthesis of a group of proteins known as heat shock (HSP) proteins. In this paper the effect of prostaglandin A (PGA ), arsenite and aspirin in Aedes albopictus cells...

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Veröffentlicht in:Zeitschrift für Naturforschung C. A journal of biosciences 2001-03, Vol.56 (3), p.298-302
Hauptverfasser: de Meneses, Marcelo D. F., Rebello, Moacyr A.
Format: Artikel
Sprache:eng
Schlagworte:
Aedes
Aedes albopictus Cells
Animals
Arsenite
Arsenites - pharmacology
Aspirin
Aspirin - pharmacology
Cell Line
Heat-Shock Proteins - biosynthesis
HSP70 Heat-Shock Proteins - biosynthesis
Immunoblotting
Methionine - metabolism
Molecular Weight
Prostaglandin
Prostaglandins A - pharmacology
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Zusammenfassung:The stress response of eukaryotic cells is characterized by changes in the metabolism of responding cells, most notably by increased synthesis of a group of proteins known as heat shock (HSP) proteins. In this paper the effect of prostaglandin A (PGA ), arsenite and aspirin in Aedes albopictus cells was investigated. In cells treated with PGA (10 μg/ml) we observed the induction of several polypeptides with molecular masses of 87, 80, 70, 57, 29 and 23 kDa. Immunoblot analysis revealed that arsenite induces a marked synthesis of HSP70, and aspirin administered during the hyperthermic treatment caused a small increase of HSP70 synthesized.
ISSN:0939-5075
1865-7125
DOI:10.1515/znc-2001-3-421