Controlled trial of intravenous immune globulin in recent-onset dilated cardiomyopathy

This prospective placebo-controlled trial was designed to determine whether intravenous immune globulin (IVIG) improves left ventricular ejection fraction (LVEF) in adults with recent onset of idiopathic dilated cardiomyopathy or myocarditis. Sixty-two patients (37 men, 25 women; mean age +/-SD 43.0...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2001-05, Vol.103 (18), p.2254-2259
Hauptverfasser:	MCNAMARA, Dennis M, HOLUBKOV, Richard, MANN, Douglas L, FELDMAN, Arthur M, STARLING, Randall C, DEC, G. William, LOH, Evan, TORRE-AMIONE, Guillermo, GASS, Alan, JANOSKO, Karen, TOKARCZYK, Tammy, KESSLER, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Biological and medical sciences Biopsy Cardiomyopathy, Dilated - complications Cardiomyopathy, Dilated - diagnosis Cardiomyopathy, Dilated - drug therapy Cohort Studies Disease-Free Survival Female Follow-Up Studies Humans Immunization, Passive Immunoglobulins, Intravenous - therapeutic use Immunomodulators Male Medical sciences Myocarditis - complications Myocarditis - diagnosis Myocarditis - drug therapy Myocardium - pathology Pharmacology. Drug treatments Prognosis Prospective Studies Stroke Volume - drug effects Treatment Outcome Ventricular Function, Left - drug effects
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Zusammenfassung:	This prospective placebo-controlled trial was designed to determine whether intravenous immune globulin (IVIG) improves left ventricular ejection fraction (LVEF) in adults with recent onset of idiopathic dilated cardiomyopathy or myocarditis. Sixty-two patients (37 men, 25 women; mean age +/-SD 43.0+/-12.3 years) with recent onset (
ISSN:	0009-7322 1524-4539
DOI:	10.1161/01.cir.103.18.2254