A direct method for the formation of peptide and carbohydrate dendrimers
Two new methods for the modification of PAMAM dendrimers have been developed which allow the covergent synthesis of either peptide or carbohydrate-bearing dendrimer molecules. Both methods involve condensation between hydroxylamino nucleophiles and appropriate carbonyl-bearing reaction partners. Two...
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| Veröffentlicht in: | Bioorganic & medicinal chemistry letters 1999-10, Vol.9 (19), p.2785-2788 |
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| container_end_page | 2788 |
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| container_issue | 19 |
| container_start_page | 2785 |
| container_title | Bioorganic & medicinal chemistry letters |
| container_volume | 9 |
| creator | Mitchell, Jeffrey P. Roberts, Kade D. Langley, Jane Koentgen, Frank Lambert, John N. |
| description | Two new methods for the modification of PAMAM dendrimers have been developed which allow the covergent synthesis of either peptide or carbohydrate-bearing dendrimer molecules. Both methods involve condensation between hydroxylamino nucleophiles and appropriate carbonyl-bearing reaction partners.
Two new methods for the modification of PAMAM dendrimers allowing short syntheses of either peptide-or carbohydrate-bearing PAMAM dendrimers. Both methods involve condensation between hydroxylamino nucleophiles and carbonyl-bearing reaction partners. |
| doi_str_mv | 10.1016/S0960-894X(99)00480-1 |
| format | Article |
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Two new methods for the modification of PAMAM dendrimers allowing short syntheses of either peptide-or carbohydrate-bearing PAMAM dendrimers. Both methods involve condensation between hydroxylamino nucleophiles and carbonyl-bearing reaction partners.</description><identifier>ISSN: 0960-894X</identifier><identifier>EISSN: 1464-3405</identifier><identifier>DOI: 10.1016/S0960-894X(99)00480-1</identifier><identifier>PMID: 10522691</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Carbohydrates - chemistry ; Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides ; Carbohydrates. Nucleosides and nucleotides ; Chemistry ; Chromatography, Gel ; Electrophoresis, Polyacrylamide Gel ; Exact sciences and technology ; Glycoconjugates - chemistry ; Molecular Sequence Data ; Molecular Structure ; Organic chemistry ; Peptides ; Peptides - chemistry ; Polyamines - chemistry ; Polymers - chemistry ; Preparations and properties</subject><ispartof>Bioorganic & medicinal chemistry letters, 1999-10, Vol.9 (19), p.2785-2788</ispartof><rights>1999</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c456t-38ec7b08e0486076c39db50a826fd3b48664dd8d82a07ddf158e3f0f473205ca3</citedby><cites>FETCH-LOGICAL-c456t-38ec7b08e0486076c39db50a826fd3b48664dd8d82a07ddf158e3f0f473205ca3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0960-894X(99)00480-1$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3549,27923,27924,45994</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1983870$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10522691$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mitchell, Jeffrey P.</creatorcontrib><creatorcontrib>Roberts, Kade D.</creatorcontrib><creatorcontrib>Langley, Jane</creatorcontrib><creatorcontrib>Koentgen, Frank</creatorcontrib><creatorcontrib>Lambert, John N.</creatorcontrib><title>A direct method for the formation of peptide and carbohydrate dendrimers</title><title>Bioorganic & medicinal chemistry letters</title><addtitle>Bioorg Med Chem Lett</addtitle><description>Two new methods for the modification of PAMAM dendrimers have been developed which allow the covergent synthesis of either peptide or carbohydrate-bearing dendrimer molecules. Both methods involve condensation between hydroxylamino nucleophiles and appropriate carbonyl-bearing reaction partners.
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| fulltext | fulltext |
| identifier | ISSN: 0960-894X |
| ispartof | Bioorganic & medicinal chemistry letters, 1999-10, Vol.9 (19), p.2785-2788 |
| issn | 0960-894X 1464-3405 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70825202 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Carbohydrates - chemistry Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides Carbohydrates. Nucleosides and nucleotides Chemistry Chromatography, Gel Electrophoresis, Polyacrylamide Gel Exact sciences and technology Glycoconjugates - chemistry Molecular Sequence Data Molecular Structure Organic chemistry Peptides Peptides - chemistry Polyamines - chemistry Polymers - chemistry Preparations and properties |
| title | A direct method for the formation of peptide and carbohydrate dendrimers |
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