Novelties in the Field of Anti-Infectives in 1998

In 1998, about 30 new medicinal chemical entities in the field of antibacterials and antifungals were presented during the 38th Interscience Conference on Antimicrobial Agents and Chemotherapy, held in San Diego. Among these compounds, only a few of them seem to be candidates for preclinical and cli...

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Veröffentlicht in:	Clinical infectious diseases 1999-09, Vol.29 (3), p.632-658
1. Verfasser:	BRYSKIER, A
Format:	Artikel
Sprache:	eng
Schlagworte:	American culture Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Anti-Infective Agents - therapeutic use Antibacterial agents Antibacterials Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Antimicrobials Biological and medical sciences Carbapenems Chemotherapy Communicable Diseases - drug therapy Dosage Drugs, Investigational - chemistry Drugs, Investigational - pharmacology Drugs, Investigational - therapeutic use Humans Infections Medical sciences Mice Microbiology Pharmacology. Drug treatments Review Article Sensitivity and Specificity
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Beschreibung
Zusammenfassung:	In 1998, about 30 new medicinal chemical entities in the field of antibacterials and antifungals were presented during the 38th Interscience Conference on Antimicrobial Agents and Chemotherapy, held in San Diego. Among these compounds, only a few of them seem to be candidates for preclinical and clinical development: GAR 936, RWJ 54,418, ME 1209, L-084, FK 483, and DC 756. Other compounds seem to be in the preselection stage or potential lead compounds.
ISSN:	1058-4838 1537-6591
DOI:	10.1086/598646