Walking ability as a measure of treatment effect in early rheumatoid arthritis

Objective: To assess the clinical usefulness of a prototype walkmat system in patients with early rheumatoid arthritis (RA). Subjects: Twenty-four subjects with early RA and symptomatic forefoot disease requiring therapy with second-line drugs were recruited. Design: Each subject underwent clinical assessment together with gait analysis on the contact sensitive walkmat system and Kistler forceplate before and after six months of treatment with second-line drugs. Two subjects were lost to follow-up. Results: There was the expected improvement in disease activity in response to therapy. Significant differences were also demonstrated in defined gait parameters that indicated improved weight-bearing and enhanced forefoot propulsion. Conclusion: Medical therapy improved walking ability in patients with RA and the walkmat system provided a useful adjunct to existing outcome measures in the assessment of lower limb function.