Hypermetabolism in the ventrolateral thalamus in unilateral Parkinsonian resting tremor: a positron emission tomography study

Tremorogenesis in Parkinson's disease (PD) is assumed to involve a cerebral network including the thalamus. An imaging study was performed on eight PD patients with strictly unilateral resting tremor using fluorodeoxyglucose positron emission tomography coregistered to 3-dimensional magnetic re...

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Veröffentlicht in:	Neuroscience letters 2001-05, Vol.304 (1), p.17-20
Hauptverfasser:	Kassubek, Jan, Juengling, Freimut D., Hellwig, Bernhard, Knauff, Markus, Spreer, Joachim, Lücking, Carl H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Fluorodeoxyglucose F18 Humans Imaging, Three-Dimensional - methods Magnetic Resonance Imaging - methods Male Medical sciences Middle Aged Neurology Parkinson Disease - diagnostic imaging Parkinson Disease - metabolism Parkinson’s disease Positron emission tomography Radiopharmaceuticals Thalamus Tomography, Emission-Computed - methods Tremor Tremor - diagnostic imaging Tremor - metabolism Ventral Thalamic Nuclei - diagnostic imaging Ventral Thalamic Nuclei - metabolism
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Zusammenfassung:	Tremorogenesis in Parkinson's disease (PD) is assumed to involve a cerebral network including the thalamus. An imaging study was performed on eight PD patients with strictly unilateral resting tremor using fluorodeoxyglucose positron emission tomography coregistered to 3-dimensional magnetic resonance imaging. Increased metabolic activity of high statistical significance ( P
ISSN:	0304-3940 1872-7972
DOI:	10.1016/S0304-3940(01)01737-2