May 1999--16 year old male with an unexpected MRI finding

Four years after resection of a supratentorial pilocytic astrocytoma this 16-year-old boy displayed widespread leptomeningeal seeding. Although the primary tumor lacked contrast enhancement, the multiple metastatic nodules were markedly contrast enhancing. Both the initial and disseminated tumor wer...

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Veröffentlicht in:Brain pathology (Zurich, Switzerland) Switzerland), 1999-10, Vol.9 (4), p.743-744
Hauptverfasser: Patt, S, Haberland, N, Graupner, H, Schreiber, D, Kalff, R
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Sprache:eng
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Zusammenfassung:Four years after resection of a supratentorial pilocytic astrocytoma this 16-year-old boy displayed widespread leptomeningeal seeding. Although the primary tumor lacked contrast enhancement, the multiple metastatic nodules were markedly contrast enhancing. Both the initial and disseminated tumor were consistent with a pilocytic astrocytoma. He was treated with vincristin and carboplatinum and the tumor was stable up to Dec. 1998. Dissemination of low-grade intracranial astrocytoma in children occurs in only 4%. It is not a sign of malignancy. The present case is similar to previously published cases. The prognosis of these patients might be quite favorable when treated with radiotherapy and/or chemotherapy.
ISSN:1015-6305