Complete Response to Topotecan of Recurrent Fallopian Tube Carcinoma

Objective. To describe the first complete response of recurrent Fallopian tube carcinoma to topotecan. Methods. A patient with recurrent Fallopian tube carcinoma previously treated with paclitaxel (Taxol) and carboplatin is described. Results. This patient demonstrated a complete clinical response t...

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Veröffentlicht in:	Gynecologic oncology 2000-01, Vol.76 (1), p.128-129
Hauptverfasser:	Dunton, Charles J., Neufeld, Julia
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic agents Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Biological and medical sciences CA-125 Antigen - analysis Chemotherapy Fallopian tube carcinoma Fallopian Tube Neoplasms - drug therapy Fallopian Tube Neoplasms - pathology Female Humans Medical sciences Pharmacology. Drug treatments topotecan Topotecan - pharmacology Topotecan - therapeutic use Treatment Outcome
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Zusammenfassung:	Objective. To describe the first complete response of recurrent Fallopian tube carcinoma to topotecan. Methods. A patient with recurrent Fallopian tube carcinoma previously treated with paclitaxel (Taxol) and carboplatin is described. Results. This patient demonstrated a complete clinical response to topotecan. Radiographic and CA-125 measurements were used to determine response. Response was noted after four cycles and a complete response demonstrated after six treatments. Conclusion. Topotecan appears active in recurrent Fallopian tube carcinoma.
ISSN:	0090-8258 1095-6859
DOI:	10.1006/gyno.1999.5630