Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin

Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin

The synthesis and biological activity of two fragments of the very potent opioid peptide biphalin, showed that Tyr-D-Ala-Gly-Phe-NH-NH

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Bibliographische Detailangaben
Veröffentlicht in:Bioorganic & medicinal chemistry letters 1999-09, Vol.9 (18), p.2763-2766
Hauptverfasser: Lipkowski, Andrzej W., Misicka, Aleksandra, Davis, Peg, Stropova, Dagmar, Janders, Jacqueline, Lachwa, Magdalena, Porreca, Frank, Yamamura, Henry I., Hruby, Victor J.
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acid Sequence
Analgesics - chemistry
Analgesics - pharmacology
Biological and medical sciences
Enkephalins - chemistry
Enkephalins - pharmacology
Medical sciences
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Peptidergic system (neuropeptide, opioid peptide, opiates...). Adenosinergic and purinergic systems
Pharmacology. Drug treatments
Receptors, Opioid, mu - drug effects
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Beschreibung
Zusammenfassung:The synthesis and biological activity of two fragments of the very potent opioid peptide biphalin, showed that Tyr-D-Ala-Gly-Phe-NH-NH
ISSN:0960-894X
1464-3405
DOI:10.1016/S0960-894X(99)00464-3