Excitation-contraction uncoupling: major role in contraction-induced muscle injury

The mechanisms that account for the strength loss after contraction-induced muscle injury remain controversial. We present data showing that (1) most of the early strength loss results from a failure of excitation-contraction coupling and (2) a slow loss of contractile protein in the days after inju...

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Veröffentlicht in:	Exercise and sport sciences reviews 2001-04, Vol.29 (2), p.82-87
Hauptverfasser:	Warren, G L, Ingalls, C P, Lowe, D A, Armstrong, R B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Exercise - physiology Humans Muscle Contraction - physiology Muscle Fibers, Skeletal - physiology Muscle Proteins - physiology Muscle, Skeletal - injuries Physical Conditioning, Animal - physiology Sarcoplasmic Reticulum - physiology Wounds and Injuries - physiopathology
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Zusammenfassung:	The mechanisms that account for the strength loss after contraction-induced muscle injury remain controversial. We present data showing that (1) most of the early strength loss results from a failure of excitation-contraction coupling and (2) a slow loss of contractile protein in the days after injury prolongs the recovery time.
ISSN:	0091-6331
DOI:	10.1097/00003677-200104000-00008