Measurement of Homonuclear Proton Couplings from Regular 2D COSY Spectra

Measurement of Homonuclear Proton Couplings from Regular 2D COSY Spectra

An interactive computer procedure is described which determines 1H–1H couplings from fitting the cross-peak multiplets in regular phase-sensitive COSY spectra. The robustness and simplicity of the method rely on the fact that a given cross-peak intensity is not an independent variable in the fitting...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of magnetic resonance (1997) 2001-04, Vol.149 (2), p.276-281
Hauptverfasser: Delaglio, Frank, Wu, Zhengrong, Bax, Ad
Format: Artikel
Sprache:eng
Schlagworte:
Computer Graphics
Fourier Analysis
Humans
Magnetic Resonance Spectroscopy - methods
Protons
Signal Processing, Computer-Assisted
Software
Ubiquitins - chemistry
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:An interactive computer procedure is described which determines 1H–1H couplings from fitting the cross-peak multiplets in regular phase-sensitive COSY spectra. The robustness and simplicity of the method rely on the fact that a given cross-peak intensity is not an independent variable in the fitting procedure, making it possible to measure couplings accurately even from individual cross peaks with unresolved multiplet structure.
ISSN:1090-7807
1096-0856
DOI:10.1006/jmre.2001.2297