Expression of chLIS1, a chicken homolog of LIS1

We have isolated the chicken LIS1 homolog, chLIS1, with DNA sequence similarity of over 68% to the human cDNA and 99% amino acid identity. Additionally, we describe the pattern of chLIS1 expression in the chicken embryo. The early embryonic expression is highly specific to the developing nervous sys...

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Veröffentlicht in:	Development genes and evolution 2000-01, Vol.210 (1), p.51-54
Hauptverfasser:	Shmueli, O, Reiner, O
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Alkyl-2-acetylglycerophosphocholine Esterase Animals Chickens DNA, Complementary - genetics DNA, Complementary - isolation & purification Humans Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - metabolism Molecular Sequence Data Nervous system Platelet Activation Sequence Homology
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Zusammenfassung:	We have isolated the chicken LIS1 homolog, chLIS1, with DNA sequence similarity of over 68% to the human cDNA and 99% amino acid identity. Additionally, we describe the pattern of chLIS1 expression in the chicken embryo. The early embryonic expression is highly specific to the developing nervous system, whereas later the expression is more widespread.
ISSN:	0949-944X 1432-041X
DOI:	10.1007/s004270050010