The effect of fish oil on hypertension, plasma lipids and hemostasis in hypertensive, obese, dyslipidemic patients with and without diabetes mellitus

The effect of fish oil on hypertension, plasma lipids and hemostasis in hypertensive, obese, dyslipidemic patients with and without diabetes mellitus

We have recently reported that dietary fish oil supplementation (n-3) polyunsaturated fatty acid (PUFA) led to a reduction in blood pressure (BP) and serum triglycerides (TG), in addition to the normalization of the hypercoagulable state in subjects with obesity, hypertension and dyslipidemia withou...

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Veröffentlicht in:Prostaglandins, leukotrienes and essential fatty acids leukotrienes and essential fatty acids, 1999-08, Vol.61 (2), p.83-87
Hauptverfasser: Yosefy, C., Reuven Viskoper, J., Laszt, A., Priluk, R., Guita, E., Varon, D., Illan, Z., Berry, E.M., Savion, N., Adan, Y., Lugassy, G., Schneider, R., Raz, A.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Biological and medical sciences
Diabetes Mellitus - diet therapy
Diet
Feeding. Feeding behavior
Female
Fish Oils - pharmacology
Fundamental and applied biological sciences. Psychology
Hemostasis - drug effects
Humans
Hyperlipidemias - diet therapy
Hypertension - diet therapy
Lipids - blood
Male
Middle Aged
Obesity - diet therapy
Proteinuria
Triglycerides - blood
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Zusammenfassung:We have recently reported that dietary fish oil supplementation (n-3) polyunsaturated fatty acid (PUFA) led to a reduction in blood pressure (BP) and serum triglycerides (TG), in addition to the normalization of the hypercoagulable state in subjects with obesity, hypertension and dyslipidemia without diabetes mellitus (OHD-DM). The aim of the present study was to explore the mechanism of this amelioration by comparing the previous results to those obtained from 19 subjects who, in addition to the conditions described above, also suffer from diabetes mellitus (OHD+DM) and proteinuria. In both the non-diabetic and diabetic groups, a similar reduction was observed in BP (from 158.7/80.8 to 146/72.9mmHg, and from 157.6/83.2 to 141.9/75.6mmHg, respectively, P
ISSN:0952-3278
1532-2823
DOI:10.1054/plef.1999.0075