Continuous glucose monitoring in patients with insulinoma

Summary Background  Insulinomas are rare neuroendocrine tumours that are usually small and may take time to localize. They cause recurrent life‐threatening spontaneous hypoglycaemia. Recurrent hypoglycaemia causes loss of hypoglycaemia awareness, putting the patient at further risk, but this has rar...

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Veröffentlicht in:Clinical endocrinology (Oxford) 2008-06, Vol.68 (6), p.912-918
Hauptverfasser: Munir, Alia, Choudhary, Pratik, Harrison, Barney, Heller, Simon, Newell-Price, John
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Sprache:eng
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Zusammenfassung:Summary Background  Insulinomas are rare neuroendocrine tumours that are usually small and may take time to localize. They cause recurrent life‐threatening spontaneous hypoglycaemia. Recurrent hypoglycaemia causes loss of hypoglycaemia awareness, putting the patient at further risk, but this has rarely been described in insulinoma. We describe the utility of continuous glucose monitoring (CGM) in patients with insulinoma. Patients and methods  Three patients, aged 72 years (patient 1), 37 years (patient 2) and 24 years (patient 3), with suspected insulinoma attended our investigation unit, in a university teaching hospital. Biochemical diagnosis was confirmed by elevated plasma insulin and C‐peptide during biochemical hypoglycaemia [plasma glucose
ISSN:0300-0664
1365-2265
DOI:10.1111/j.1365-2265.2007.03161.x