The Effect of Restorative Proctocolectomy on Sexual Function, Urinary Function, Fertility, Pregnancy and Delivery: A Systematic Review

PURPOSE: METHODS: RESULTS:A total of 22 studies, with 1,852 females, were included. Infertility rate was 12 percent before restorative proctocolectomy and 26 percent after, among 945 patients in seven studies. The incidence of sexual dysfunction was 8 percent preoperatively and 25 percent postoperat...

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Veröffentlicht in:Diseases of the colon & rectum 2007-08, Vol.50 (8), p.1128-1138
Hauptverfasser: Cornish, Julie A, Tan, Emile, Teare, Julian, Teoh, Teoh G, Rai, Raj, Darzi, Ara W, Paraskevas, Paraskeva, Clark, Susan K, Tekkis, Paris P
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Sprache:eng
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Zusammenfassung:PURPOSE: METHODS: RESULTS:A total of 22 studies, with 1,852 females, were included. Infertility rate was 12 percent before restorative proctocolectomy and 26 percent after, among 945 patients in seven studies. The incidence of sexual dysfunction was 8 percent preoperatively and 25 percent postoperatively (7 studies, n = 419). Two studies (n = 62) reported no urinary dysfunction in patients undergoing restorative proctocolectomy. There was an increased incidence of cesarean section after restorative proctocolectomy. During the third trimester of pregnancy, there was an increase in stool frequency by 1.15 stools per day compared with before pregnancy frequency (n = 49 95 percent confidence interval, 0.28-2.03 P = 0.01 chi-squared statistic, 0.04 P = 0.84). No significant differences were seen in pouch function after vaginal delivery (n = 456; weighted mean difference, 0.23; 95 percent confidence interval, 0.43-0.88; P = 0.49; chi-squared statistic, 1.29; P = 0.26). CONCLUSIONS:
ISSN:0012-3706
1530-0358
DOI:10.1007/s10350-007-0240-7