New 14-hydroxy-taxane and 2alpha,20-epoxy-11(15-1)abeotaxane from the needles of Taxus canadensis

Two new taxanes were isolated from the needles of Taxus canadensis. Their structures were established as 10beta,13alpha-diacetoxytaxa-4(20),11-diene-5alpha,9alpha,14beta-triol (1) and 4alpha,13alpha-diacetoxy-2alpha,20-epoxy-11(15-1)abeotaxa-11,15-diene-5alpha,7beta,9alpha,10beta-tetraol (2) on the...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2007-07, Vol.71 (7), p.1777-1780
Hauptverfasser:	Shi, Q.W.(Hebei Medical Univ., Shijiazhuang (China)), Dong, M, Huo, C.H, Su, X.H, Li, C.F, Zhang, X.P, Wang, Y.F, Kiyota, H
Format:	Artikel
Sprache:	eng
Schlagworte:	AISLAMIENTO Diterpenes - chemistry Diterpenes - isolation & purification DITERPENOIDE DITERPENOIDS DITERPENOS DRUG PLANTS Epoxy Compounds - chemistry Epoxy Compounds - isolation & purification FEUILLE HOJAS ISOLATION ISOLEMENT LEAVES Plant Leaves - chemistry PLANTAS MEDICINALES PLANTE MEDICINALE Taxoids - chemistry Taxoids - isolation & purification TAXUS Taxus - chemistry
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Zusammenfassung:	Two new taxanes were isolated from the needles of Taxus canadensis. Their structures were established as 10beta,13alpha-diacetoxytaxa-4(20),11-diene-5alpha,9alpha,14beta-triol (1) and 4alpha,13alpha-diacetoxy-2alpha,20-epoxy-11(15-1)abeotaxa-11,15-diene-5alpha,7beta,9alpha,10beta-tetraol (2) on the basis of a spectroscopic analysis.
ISSN:	0916-8451 1347-6947