Cognitive and psychosocial features of childhood and juvenile MS

To assess the impact of multiple sclerosis (MS) on cognitive and psychosocial functioning in childhood and juvenile cases. We used an extensive neuropsychological battery assessing IQ, memory, attention/concentration, executive functions, and language. Fatigue and depression were also measured. An interview on school and daily living activities was obtained from the parents. Performance of cases was compared with that of demographically matched healthy controls. Sixty-three patients and 57 healthy controls were assessed. Five patients (8%) exhibited a particularly low IQ (