Long-term outcome of two forms of randomised benzodiazepine discontinuation
Abouttwo-thirds of long-term users of benzodiazepines in the population are able to discontinue this drug with the aid of supervised programmes for tapering off. Little is known about the long-term outcome of such programmes, and they have never been compared with usual care. After a 15-month follow...
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| Veröffentlicht in: | British journal of psychiatry 2006-02, Vol.188 (2), p.188-189 |
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| container_title | British journal of psychiatry |
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| creator | Voshaar, R. C. Oude Gorgels, W. J. M. J. Mol, A. J. J. Van Balkom, A. J. L. M. Mulder, J. Van De Lisdonk, E. H. Breteler, M. H. M. Zitman, F. G. |
| description | Abouttwo-thirds of long-term users of benzodiazepines in the population are
able to discontinue this drug with the aid of supervised programmes for
tapering off. Little is known about the long-term outcome of such
programmes, and they have never been compared with usual care. After a
15-month follow-up of a randomised controlled trial comparing such a
programme with and without psychotherapy with usual care, we found
significantly higher longitudinal abstinence rates in long-term
benzodiazepine users who received a benzodiazepine tapering-off programme
without psychotherapy (25 out of 69, 36%) compared with those who received
usual care (5 out of 33, 15%; P=0.03). |
| doi_str_mv | 10.1192/bjp.bp.105.012039 |
| format | Article |
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able to discontinue this drug with the aid of supervised programmes for
tapering off. Little is known about the long-term outcome of such
programmes, and they have never been compared with usual care. After a
15-month follow-up of a randomised controlled trial comparing such a
programme with and without psychotherapy with usual care, we found
significantly higher longitudinal abstinence rates in long-term
benzodiazepine users who received a benzodiazepine tapering-off programme
without psychotherapy (25 out of 69, 36%) compared with those who received
usual care (5 out of 33, 15%; P=0.03).</description><identifier>ISSN: 0007-1250</identifier><identifier>EISSN: 1472-1465</identifier><identifier>DOI: 10.1192/bjp.bp.105.012039</identifier><identifier>PMID: 16449709</identifier><identifier>CODEN: BJPYAJ</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Abstinence ; Anti-Anxiety Agents - administration & dosage ; Benzodiazepines ; Benzodiazepines - administration & dosage ; Clinical outcomes ; Cognitive Therapy - methods ; Combined Modality Therapy - methods ; Female ; Follow-Up Studies ; Humans ; Long-Term Care ; Male ; Middle Aged ; Randomized controlled trials ; Short Reports ; Treatment Outcome ; Withdrawal</subject><ispartof>British journal of psychiatry, 2006-02, Vol.188 (2), p.188-189</ispartof><rights>Copyright © 2006 The Royal College of Psychiatrists</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443t-96e2bde94cee4d0e298ba279912b35add18a518a4901ad4d3c996feecf7760693</citedby><cites>FETCH-LOGICAL-c443t-96e2bde94cee4d0e298ba279912b35add18a518a4901ad4d3c996feecf7760693</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0007125000169685/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,776,780,27901,27902,30977,55603</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16449709$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Voshaar, R. C. Oude</creatorcontrib><creatorcontrib>Gorgels, W. J. M. J.</creatorcontrib><creatorcontrib>Mol, A. J. J.</creatorcontrib><creatorcontrib>Van Balkom, A. J. L. M.</creatorcontrib><creatorcontrib>Mulder, J.</creatorcontrib><creatorcontrib>Van De Lisdonk, E. H.</creatorcontrib><creatorcontrib>Breteler, M. H. M.</creatorcontrib><creatorcontrib>Zitman, F. G.</creatorcontrib><title>Long-term outcome of two forms of randomised benzodiazepine discontinuation</title><title>British journal of psychiatry</title><addtitle>Br J Psychiatry</addtitle><description>Abouttwo-thirds of long-term users of benzodiazepines in the population are
able to discontinue this drug with the aid of supervised programmes for
tapering off. Little is known about the long-term outcome of such
programmes, and they have never been compared with usual care. After a
15-month follow-up of a randomised controlled trial comparing such a
programme with and without psychotherapy with usual care, we found
significantly higher longitudinal abstinence rates in long-term
benzodiazepine users who received a benzodiazepine tapering-off programme
without psychotherapy (25 out of 69, 36%) compared with those who received
usual care (5 out of 33, 15%; P=0.03).</description><subject>Abstinence</subject><subject>Anti-Anxiety Agents - administration & dosage</subject><subject>Benzodiazepines</subject><subject>Benzodiazepines - administration & dosage</subject><subject>Clinical outcomes</subject><subject>Cognitive Therapy - methods</subject><subject>Combined Modality Therapy - methods</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Long-Term Care</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Randomized controlled trials</subject><subject>Short Reports</subject><subject>Treatment Outcome</subject><subject>Withdrawal</subject><issn>0007-1250</issn><issn>1472-1465</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqFkE1r3DAQhkVJabZpf0Avxb305o1Gli3rGEKali7k0p6FPsa7WtaSI9mE5NdXyy7k1hxGwwvPzIiHkC9A1wCSXZv9tDbTGmi7psBoI9-RFXDBauBde0FWlFJRA2vpJfmY877EhjPxgVxCx7kUVK7I700M23rGNFZxmW0csYpDNT_FaohpzMeQdHBx9BldZTC8ROf1C04-YOV8tjHMPix69jF8Iu8Hfcj4-dyvyN8fd39uf9abh_tftzeb2nLezLXskBmHkltE7igy2RvNhJTATNNq56DXbSkuKWjHXWOl7AZEOwjR0U42V-T7ae-U4uOCeVbldxYPBx0wLlkJKhgDxt4EWwGF7I8gnECbYs4JBzUlP-r0rICqo2pVVCszldiqk-oy8_W8fDEjuteJs9sCfDsBO7_dPfmEKtkpP9udgr5X7PgWpjkf1qNJ3m1R7eOSQtH3n9P_AOBgl-4</recordid><startdate>200602</startdate><enddate>200602</enddate><creator>Voshaar, R. C. Oude</creator><creator>Gorgels, W. J. M. J.</creator><creator>Mol, A. J. J.</creator><creator>Van Balkom, A. J. L. M.</creator><creator>Mulder, J.</creator><creator>Van De Lisdonk, E. H.</creator><creator>Breteler, M. H. M.</creator><creator>Zitman, F. G.</creator><general>Cambridge University Press</general><general>RCP</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7X8</scope></search><sort><creationdate>200602</creationdate><title>Long-term outcome of two forms of randomised benzodiazepine discontinuation</title><author>Voshaar, R. C. Oude ; Gorgels, W. J. M. J. ; Mol, A. J. J. ; Van Balkom, A. J. L. M. ; Mulder, J. ; Van De Lisdonk, E. H. ; Breteler, M. H. M. ; Zitman, F. G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c443t-96e2bde94cee4d0e298ba279912b35add18a518a4901ad4d3c996feecf7760693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Abstinence</topic><topic>Anti-Anxiety Agents - administration & dosage</topic><topic>Benzodiazepines</topic><topic>Benzodiazepines - administration & dosage</topic><topic>Clinical outcomes</topic><topic>Cognitive Therapy - methods</topic><topic>Combined Modality Therapy - methods</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Long-Term Care</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Randomized controlled trials</topic><topic>Short Reports</topic><topic>Treatment Outcome</topic><topic>Withdrawal</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Voshaar, R. C. Oude</creatorcontrib><creatorcontrib>Gorgels, W. J. M. J.</creatorcontrib><creatorcontrib>Mol, A. J. J.</creatorcontrib><creatorcontrib>Van Balkom, A. J. L. M.</creatorcontrib><creatorcontrib>Mulder, J.</creatorcontrib><creatorcontrib>Van De Lisdonk, E. H.</creatorcontrib><creatorcontrib>Breteler, M. H. M.</creatorcontrib><creatorcontrib>Zitman, F. G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Voshaar, R. C. Oude</au><au>Gorgels, W. J. M. J.</au><au>Mol, A. J. J.</au><au>Van Balkom, A. J. L. M.</au><au>Mulder, J.</au><au>Van De Lisdonk, E. H.</au><au>Breteler, M. H. M.</au><au>Zitman, F. G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term outcome of two forms of randomised benzodiazepine discontinuation</atitle><jtitle>British journal of psychiatry</jtitle><addtitle>Br J Psychiatry</addtitle><date>2006-02</date><risdate>2006</risdate><volume>188</volume><issue>2</issue><spage>188</spage><epage>189</epage><pages>188-189</pages><issn>0007-1250</issn><eissn>1472-1465</eissn><coden>BJPYAJ</coden><abstract>Abouttwo-thirds of long-term users of benzodiazepines in the population are
able to discontinue this drug with the aid of supervised programmes for
tapering off. Little is known about the long-term outcome of such
programmes, and they have never been compared with usual care. After a
15-month follow-up of a randomised controlled trial comparing such a
programme with and without psychotherapy with usual care, we found
significantly higher longitudinal abstinence rates in long-term
benzodiazepine users who received a benzodiazepine tapering-off programme
without psychotherapy (25 out of 69, 36%) compared with those who received
usual care (5 out of 33, 15%; P=0.03).</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>16449709</pmid><doi>10.1192/bjp.bp.105.012039</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | British journal of psychiatry, 2006-02, Vol.188 (2), p.188-189 |
| issn | 0007-1250 1472-1465 |
| language | eng |
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| source | Applied Social Sciences Index & Abstracts (ASSIA); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Cambridge Journals; Alma/SFX Local Collection |
| subjects | Abstinence Anti-Anxiety Agents - administration & dosage Benzodiazepines Benzodiazepines - administration & dosage Clinical outcomes Cognitive Therapy - methods Combined Modality Therapy - methods Female Follow-Up Studies Humans Long-Term Care Male Middle Aged Randomized controlled trials Short Reports Treatment Outcome Withdrawal |
| title | Long-term outcome of two forms of randomised benzodiazepine discontinuation |
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