Long-term outcome of two forms of randomised benzodiazepine discontinuation

Abouttwo-thirds of long-term users of benzodiazepines in the population are able to discontinue this drug with the aid of supervised programmes for tapering off. Little is known about the long-term outcome of such programmes, and they have never been compared with usual care. After a 15-month follow...

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Veröffentlicht in:British journal of psychiatry 2006-02, Vol.188 (2), p.188-189
Hauptverfasser: Voshaar, R. C. Oude, Gorgels, W. J. M. J., Mol, A. J. J., Van Balkom, A. J. L. M., Mulder, J., Van De Lisdonk, E. H., Breteler, M. H. M., Zitman, F. G.
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Sprache:eng
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Zusammenfassung:Abouttwo-thirds of long-term users of benzodiazepines in the population are able to discontinue this drug with the aid of supervised programmes for tapering off. Little is known about the long-term outcome of such programmes, and they have never been compared with usual care. After a 15-month follow-up of a randomised controlled trial comparing such a programme with and without psychotherapy with usual care, we found significantly higher longitudinal abstinence rates in long-term benzodiazepine users who received a benzodiazepine tapering-off programme without psychotherapy (25 out of 69, 36%) compared with those who received usual care (5 out of 33, 15%; P=0.03).
ISSN:0007-1250
1472-1465
DOI:10.1192/bjp.bp.105.012039