Nonpeptidic Ligands for Peptide-Activated G Protein-Coupled Receptors

Nonpeptidic Ligands for Peptide-Activated G Protein-Coupled Receptors

Nonpeptidic ligands for G protein-coupled receptors activated by peptides are discussed. An examination of their pharmacological properties is presented.

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Veröffentlicht in:Chemical reviews 2007-07, Vol.107 (7), p.2960-3041
Hauptverfasser: Blakeney, Jade S, Reid, Robert C, Le, Giang T, Fairlie, David P
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biochemistry
Drug Evaluation
Humans
Ligands
Peptides
Peptides - chemistry
Peptides - metabolism
Pharmacology
Proteins
Receptors, Cell Surface - chemistry
Receptors, Cell Surface - metabolism
Receptors, G-Protein-Coupled - chemistry
Receptors, G-Protein-Coupled - metabolism
Structure-Activity Relationship
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Beschreibung
Zusammenfassung:Nonpeptidic ligands for G protein-coupled receptors activated by peptides are discussed. An examination of their pharmacological properties is presented.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr050984g