Telencephalic oligodendrocytes battle it out

Telencephalic oligodendrocytes battle it out

The exact embryonic origins of forebrain oligodendrocytes have been unclear. A new study addresses the question with elegant genetic fate mapping, and concludes that oligodendrocytes are generated in three distinct waves. Oligodendrocytes from later waves eventually replaced those generated in earli...

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Veröffentlicht in:Nature neuroscience 2006-02, Vol.9 (2), p.153-154
Hauptverfasser: Ventura, Rachel E, Goldman, James E
Format: Artikel
Sprache:eng
Schlagworte:
Animal Genetics and Genomics
Animals
Behavioral Sciences
Biological Techniques
Biomedical and Life Sciences
Biomedicine
Cell Lineage
Embryo, Mammalian
Embryonic development
Genetic aspects
Humans
Neurobiology
Neurosciences
news-and-views
Oligodendroglia
Oligodendroglia - cytology
Stem Cells - cytology
Telencephalon - cytology
Telencephalon - growth & development
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Beschreibung
Zusammenfassung:The exact embryonic origins of forebrain oligodendrocytes have been unclear. A new study addresses the question with elegant genetic fate mapping, and concludes that oligodendrocytes are generated in three distinct waves. Oligodendrocytes from later waves eventually replaced those generated in earlier waves, but if one wave was lost, the other waves could compensate.
ISSN:1097-6256
1546-1726
DOI:10.1038/nn0206-153