Striatal D2 receptor binding as a marker of prognosis and outcome in untreated first-episode psychosis

In a preliminary 123I-IBZM SPECT study in first-episode psychosis, a relationship between striatal dopaminergic D2 receptor (D2R) binding and premorbid adjustment was suggested. These results were replicated in the present study ( n = 18), and D2R binding at diagnosis predicted a high probability fo...

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Veröffentlicht in:	NeuroImage (Orlando, Fla.) Fla.), 2006-01, Vol.29 (2), p.662-666
Hauptverfasser:	Corripio, Iluminada, Pérez, Víctor, Catafau, Ana M., Mena, Esther, Carrió, Ignasi, Alvarez, Enric
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Antipsychotic Agents - therapeutic use Benzamides Biomarkers Case-Control Studies Dopamine Dopamine receptors Female First-episode psychosis Hospitals Humans Hypotheses Logistics Male Medical imaging Medical prognosis Multivariate analysis Neostriatum - diagnostic imaging Neostriatum - metabolism Outcome Premorbid adaptation Prognosis Prospective Studies Psychiatric Status Rating Scales Psychiatry Psychosis Psychotic Disorders - diagnostic imaging Psychotic Disorders - drug therapy Psychotic Disorders - metabolism Pyrrolidines Radiopharmaceuticals Ratios Receptors, Dopamine D2 - metabolism Schizophrenia SPECT Studies Tomography, Emission-Computed, Single-Photon Treatment Outcome
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