Pretransplantation Consolidation Chemotherapy Decreases Leukemia Relapse after Autologous Blood and Bone Marrow Transplants for Acute Myelogenous Leukemia in First Remission

Controversy exists over whether pretransplantation consolidation chemotherapy affects the outcome of subsequent autotransplantation for acute myelogenous leukemia (AML). The current study was undertaken to determine the association between previous consolidation and outcome of autotransplantation fo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biology of blood and marrow transplantation 2006-02, Vol.12 (2), p.204-216
Hauptverfasser:	Tallman, Martin S., Pérez, Waleska S., Lazarus, Hillard M., Gale, Robert Peter, Maziarz, Richard T., Rowe, Jacob M., Marks, David I., Cahn, Jean-Yves, Bashey, Asad, Bishop, Michael R., Christiansen, Neal, Frankel, Stanley R., García, Juan J., Ilhan, Osman, Laughlin, Mary J., Liesveld, Jane, Linker, Charles, Litzow, Mark R., Luger, Selina, McCarthy, Philip L., Milone, Gustavo A., Pavlovsky, Santiago, Phillips, Gordon L., Russell, James A., Saez, Ruben A., Schiller, Gary, Sierra, Jorge, Weiner, Roy S., Zander, Axel R., Zhang, Mei-Jie, Keating, Armand, Weisdorf, Daniel J., Horowitz, Mary M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myelogenous leukemia Adolescent Adult Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage Autologous Autotransplantation Bone Marrow Transplantation - mortality Child Child, Preschool Consolidation Disease-Free Survival Female Humans Infant Leukemia, Myeloid, Acute - mortality Leukemia, Myeloid, Acute - therapy Male Middle Aged Remission Induction Retrospective Studies Survival Rate Transplantation Transplantation, Autologous
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Controversy exists over whether pretransplantation consolidation chemotherapy affects the outcome of subsequent autotransplantation for acute myelogenous leukemia (AML). The current study was undertaken to determine the association between previous consolidation and outcome of autotransplantation for AML in first remission. Posttransplantation outcomes of 146 patients receiving no consolidation were compared with those of 244 patients receiving standard-dose (
ISSN:	1083-8791 1523-6536
DOI:	10.1016/j.bbmt.2005.10.013