Rationale and Design for the Blood Pressure Intervention of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial

The Action to Control Cardiovascular Disease in Diabetes (ACCORD) blood pressure trial is an unmasked, open-label, randomized trial with a sample size of 4,733 participants. This report describes the rationale, design, and methods of the blood pressure interventions in ACCORD. Participants eligible...

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Veröffentlicht in:	The American journal of cardiology 2007-06, Vol.99 (12), p.S44-S55
Hauptverfasser:	Cushman, William C., MD, Grimm, Richard H., MD, PhD, Cutler, Jeffrey A., MD, MPH, Evans, Gregory W., MS, Capes, Sarah, MD, Corson, Marshall A., MD, Sadler, Laurie S., MD, Alderman, Michael H., MD, Peterson, Kevin, MD, Bertoni, Alain, MD, MPH, Basile, Jan N., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Antihypertensive Agents - therapeutic use Blood Pressure Cardiology Cardiovascular Cardiovascular disease Clinical outcomes Clinical trials Coronary Artery Disease - blood Coronary Artery Disease - prevention & control Diabetes Diabetes Mellitus, Type 2 Diabetic Angiopathies - blood Diabetic Angiopathies - prevention & control Humans Hypertension - blood Hypertension - prevention & control Patient Selection Randomized Controlled Trials as Topic Research Design Risk factors
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Beschreibung
Zusammenfassung:	The Action to Control Cardiovascular Disease in Diabetes (ACCORD) blood pressure trial is an unmasked, open-label, randomized trial with a sample size of 4,733 participants. This report describes the rationale, design, and methods of the blood pressure interventions in ACCORD. Participants eligible for the blood pressure trial are randomized to 1 of 2 groups with different treatment goals: systolic blood pressure
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2007.03.005