Non-haem iron transport in the rat proximal colon

Background Only 10% of dietary iron is absorbed in the duodenum which implies that 90% (approximately 9 mg day−1) reaches the lower small intestine and colon. Therefore the purpose of this study was to assess the iron transport capacity of the rat proximal colon and to determine whether iron absorp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of clinical investigation 2006-01, Vol.36 (1), p.35-40
Hauptverfasser:	Johnston, K. L., Johnson, D. M., Marks, J., Srai, S. K., Debnam, E. S., Sharp, P. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological Transport Blotting, Western Cation Transport Proteins - metabolism Colon - metabolism DMT1 Duodenum - metabolism General aspects Heme Intestinal Absorption Intestinal Mucosa - metabolism IREG1 Iron - blood Iron - deficiency iron transport Iron, Dietary - administration & dosage Iron, Dietary - pharmacokinetics Iron-Binding Proteins - metabolism Male Medical sciences Metabolic diseases Metals (hemochromatosis...) Other metabolic disorders proximal colon Rats Rats, Wistar
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Background Only 10% of dietary iron is absorbed in the duodenum which implies that 90% (approximately 9 mg day−1) reaches the lower small intestine and colon. Therefore the purpose of this study was to assess the iron transport capacity of the rat proximal colon and to determine whether iron absorption is regulated by changes in dietary iron content. Materials and methods Rats were fed for 14 days on either iron adequate (44 mg Fe kg−1 diet) or iron‐deficient (
ISSN:	0014-2972 1365-2362
DOI:	10.1111/j.1365-2362.2006.01585.x