Association between IgE levels and asthma severity among African American, Mexican, and Puerto Rican patients with asthma

Association between IgE levels and asthma severity among African American, Mexican, and Puerto Rican patients with asthma

Background High levels of IgE are associated with asthma. Whether higher levels of IgE are associated with more severe asthma is still unclear. Objective To determine whether IgE is associated with asthma severity among Latino and African American subjects with asthma. Methods We assessed lung funct...

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Veröffentlicht in:Journal of allergy and clinical immunology 2007-07, Vol.120 (1), p.137-143
Hauptverfasser: Naqvi, Mariam, BA, Choudhry, Shweta, PhD, MSc, Tsai, Hui-Ju, PhD, Thyne, Shannon, MD, Navarro, Daniel, MD, Nazario, Sylvette, MD, Rodriguez-Santana, Jose R., MD, Casal, Jesus, MD, Torres, Alfonso, MD, Chapela, Rocio, MD, Watson, H. Geoffrey, MD, Meade, Kelley, MD, Rodriguez-Cintron, William, MD, LeNoir, Michael, MD, Avila, Pedro C., MD, Burchard, Esteban González, MD, MPH
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
African Americans
Allergies
allergy
Allergy and Immunology
Asthma
Asthma - diagnosis
Asthma - ethnology
Biological and medical sciences
Child
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Humans
IgE
Immunoglobulin E - blood
Medical sciences
Mexicans
Mexico
Mortality
Puerto Ricans
Puerto Rico
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
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Beschreibung
Zusammenfassung:Background High levels of IgE are associated with asthma. Whether higher levels of IgE are associated with more severe asthma is still unclear. Objective To determine whether IgE is associated with asthma severity among Latino and African American subjects with asthma. Methods We assessed lung function and asthma severity among African American, Mexican, and Puerto Rican patients with asthma with high IgE levels (≥100 IU/mL; n = 492) and compared these values to those of patients with asthma with low IgE levels (
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2007.02.045