Insulin resistance, inflammation, and the metabolic syndrome following roux-en-Y gastric bypass surgery in severely obese subjects

Insulin resistance, inflammation, and the metabolic syndrome following roux-en-Y gastric bypass surgery in severely obese subjects

The aim of our study was to evaluate the time course of metabolic syndrome components, insulin sensitivity and inflammatory markers, following laparoscopic RYGBP in severely obese subjects. HOMA-IR significantly correlated with fasting plasma glucose (FPG) (r = 0.659, P < 0.001) and tended to cor...

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Veröffentlicht in:Diabetes care 2007-07, Vol.30 (7), p.1906-1908
Hauptverfasser: MORINIGO, Rosa, CASAMITJANA, Roser, DELGADO, Salvadora, LACY, Antonio, DEULOFEU, Ramon, CONGET, Ignacio, BARCELO-BATLLORI, Silvia, GOMIS, Ramon, VIDAL, Josep
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biological and medical sciences
Care and treatment
Complications and side effects
Diabetes
Endocrinopathies
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Gastric Bypass
Gastrointestinal surgery
Health aspects
Humans
Inflammation
Inflammation - etiology
Insulin
Insulin Resistance
Laparoscopy
Male
Medical sciences
Metabolic syndrome
Metabolic Syndrome - etiology
Metabolic syndrome X
Metabolism
Middle Aged
Nutrition
Obesity
Obesity, Morbid - complications
Obesity, Morbid - surgery
Overweight persons
Postoperative Period
Risk factors
Studies
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vertebrates: endocrinology
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Zusammenfassung:The aim of our study was to evaluate the time course of metabolic syndrome components, insulin sensitivity and inflammatory markers, following laparoscopic RYGBP in severely obese subjects. HOMA-IR significantly correlated with fasting plasma glucose (FPG) (r = 0.659, P < 0.001) and tended to correlate with systolic blood pressure (P = 0.071) and waist circumference (P = 0.074), albeit it did not reach statistical significance.
ISSN:0149-5992
1935-5548
DOI:10.2337/dc07-0189