Peptaibiotics and Peptaibols: An Alternative to Classical Antibiotics?

Peptaibiotics and Peptaibols: An Alternative to Classical Antibiotics?

The development and antimicrobial properties of peptaibiotics and peptaibols are discussed. Also, the role of emerging peptaibol analogues, of alamethicin, e.g., harzianins HC, trichotoxin, and antiamoebin, is outlined.

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Bibliographische Detailangaben
Veröffentlicht in:Chemistry & biodiversity 2007-06, Vol.4 (6), p.1023-1026
1. Verfasser: Duclohier, Hervé
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Antimicrobial peptides
Peptaibiotics
Peptaibols
Peptides
Permeability assays
Planar lipid bilayers
Structure-Activity Relationship
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Zusammenfassung:The development and antimicrobial properties of peptaibiotics and peptaibols are discussed. Also, the role of emerging peptaibol analogues, of alamethicin, e.g., harzianins HC, trichotoxin, and antiamoebin, is outlined.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.200790094