Human Placenta in Gestational Diabetes Mellitus: The insulin and cytokine network

[...] the maternal-fetal control of the placenta is a cumulative result of cell cooperation that may propagate a vicious cycle for enhancement of cytokine production, which may eventually have an impact on insulin action in the fetoplacental unit and possibly obesity in utero.

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Bibliographische Detailangaben
Veröffentlicht in:	Diabetes care 2007-07, Vol.30 (7), p.S120-S126
Hauptverfasser:	Desoye, Gernot, Hauguel-de Mouzon, Sylvie
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Biological and medical sciences Care and treatment Cytokines Cytokines - physiology Diabetes Diabetes in pregnancy Diabetes, Gestational - physiopathology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Female Gene expression Health aspects Humans Hyperglycemia Insulin resistance Medical sciences Metabolic diseases Miscellaneous Placenta Placenta - immunology Placenta - metabolism Pregnancy Public health. Hygiene Public health. Hygiene-occupational medicine Receptor, Insulin - physiology Tissues
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Beschreibung
Zusammenfassung:	[...] the maternal-fetal control of the placenta is a cumulative result of cell cooperation that may propagate a vicious cycle for enhancement of cytokine production, which may eventually have an impact on insulin action in the fetoplacental unit and possibly obesity in utero.
ISSN:	0149-5992 1935-5548
DOI:	10.2337/dc07-s203