Clozapine for the treatment of neurogenic bladder

Neurogenic bladder leading to urinary incontinence has been described in patients of stroke, dementia, Parkinson's disease, and some schizophrenia cases with cognitive impairment possibly due to impaired cortical inhibition of the urinary bladder. The underlying brain abnormalities for urinary...

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Veröffentlicht in:	Neurourology and urodynamics 2007-01, Vol.26 (4), p.537-539
Hauptverfasser:	Kumar, Amardeep, Chadda, R.K., Kumar, Nand, Balan, Sabish, Prakash Srinivasan, Shiva
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antipsychotic Agents - therapeutic use bladder clozapine Clozapine - therapeutic use Humans Male neurogenic Radionuclide Imaging Schizophrenia - complications Schizophrenia - drug therapy Schizophrenic Psychology urge incontinence Urinary Bladder, Neurogenic - diagnostic imaging Urinary Bladder, Neurogenic - drug therapy Urinary Incontinence, Urge - complications Urinary Incontinence, Urge - diagnostic imaging Urinary Incontinence, Urge - drug therapy Urodynamics
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Zusammenfassung:	Neurogenic bladder leading to urinary incontinence has been described in patients of stroke, dementia, Parkinson's disease, and some schizophrenia cases with cognitive impairment possibly due to impaired cortical inhibition of the urinary bladder. The underlying brain abnormalities for urinary incontinence are similar in such cases. We report here such a case of neurogenic bladder responding to treatment with clozapine. The possible mechanism of action and clinical implications are described. Neurourol. Urodynam. 26:537–539, 2007. © 2007 Wiley‐Liss, Inc.
ISSN:	0733-2467 1520-6777
DOI:	10.1002/nau.20399