Anti-inflammatory effect of (+)-pinitol

In the carrageenin-induced paw oedema in rats, (+)-pinitol (2.5–10 mg/kg, i.p.), isolated from Abies pindrow leaves, showed a significant anti-inflammatory effect, the highest dose being comparable to phenylbutazone (100 mg/kg, i.p.).

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Bibliographische Detailangaben
Veröffentlicht in:	Fitoterapia 2001-02, Vol.72 (2), p.168-170
Hauptverfasser:	Singh, R.K., Pandey, B.L., Tripathi, M., Pandey, V.B.
Format:	Artikel
Sprache:	eng
Schlagworte:	(+)-Pinitol Abies pindrow Animals Anti-inflammatory activity Anti-Inflammatory Agents - pharmacology Biological and medical sciences Carrageenan Dose-Response Relationship, Drug Edema - chemically induced Edema - prevention & control Female General pharmacology Inositol - analogs & derivatives Inositol - pharmacology Male Medical sciences Mice Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology Plant Leaves Plants, Medicinal Rats Rats, Wistar
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Beschreibung
Zusammenfassung:	In the carrageenin-induced paw oedema in rats, (+)-pinitol (2.5–10 mg/kg, i.p.), isolated from Abies pindrow leaves, showed a significant anti-inflammatory effect, the highest dose being comparable to phenylbutazone (100 mg/kg, i.p.).
ISSN:	0367-326X
DOI:	10.1016/S0367-326X(00)00267-7