No Beneficial Effect of Interferon-γ Treatment in 2 Human Immunodeficiency Virus-Infected Patients with Mycobacterium avium Complex Infection

Two human immunodeficiency virus-infected patients with refractory disseminated Mycobacterium avium complex infection were treated with recombinant interferon-γ (IFN-γ) given subcutaneously for 3 and 4 months, respectively. Although both patients demonstrated some clinical improvement initially, IFN...

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Veröffentlicht in:	Clinical infectious diseases 2001-02, Vol.32 (4), p.e81-e82
Hauptverfasser:	Lauw, Fanny N., van der Meer, Jan T. M., de Metz, Jesse, Danner, Sven A., van der Poll, Tom
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS-Related Opportunistic Infections - drug therapy AIDS-Related Opportunistic Infections - microbiology Female Human immunodeficiency virus Humans Interferon-gamma - therapeutic use Male Mycobacterium avium Mycobacterium avium Complex Mycobacterium avium-intracellulare Infection - drug therapy Mycobacterium avium-intracellulare Infection - microbiology Treatment Outcome
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Beschreibung
Zusammenfassung:	Two human immunodeficiency virus-infected patients with refractory disseminated Mycobacterium avium complex infection were treated with recombinant interferon-γ (IFN-γ) given subcutaneously for 3 and 4 months, respectively. Although both patients demonstrated some clinical improvement initially, IFN-γ therapy did not produce sustained benefit.
ISSN:	1058-4838 1537-6591
DOI:	10.1086/318705