Alterations of lipolytic enzymes and high-density lipoprotein subfractions induced by physical activity in type 2 diabetes mellitus

Objective This study investigates the effects of regular moderate physical activity on lipolytic enzymes and plasma lipid concentration, particularly high‐density lipoprotein cholesterol (HDL‐C) subfractions, in patients with type 2 diabetes mellitus. Ten patients participated in a 3‐month exercise programme without any changes in current medical therapy. The control group consisted of six patients who were matched with regard to sex, age, diabetes duration and diabetes therapy. Results Mean (± SE) physical activity in the intervention group increased from 70 ± 21 to 220 ± 28 min per week, which resulted in an increase in total HDL‐C from 1·04 ± 0·07 to 1·28 ± 0·12 (P