Remifentanil Halves the EC50 of Propofol for Successful Insertion of the Laryngeal Mask Airway and Laryngeal Tube in Pediatric Patients

Remifentanil Halves the EC50 of Propofol for Successful Insertion of the Laryngeal Mask Airway and Laryngeal Tube in Pediatric Patients

Propofol and remifentanil are the drugs of choice for insertion of the supraglottic airway without muscle relaxants for short duration surgery. In this study, we compared propofol concentrations required for insertion of laryngeal mask way (LMA) or laryngeal tube (LT) with and without remifentanil....

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Veröffentlicht in:Anesthesia and analgesia 2007-07, Vol.105 (1), p.57-61
Hauptverfasser: Park, Hye-Jin, Lee, Jeong-Rim, Kim, Chong Sung, Kim, Seong Deok, Kim, Hee-Soo
Format: Artikel
Sprache:eng
Schlagworte:
Age Factors
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Child
Child, Preschool
Dose-Response Relationship, Drug
Double-Blind Method
Humans
Intubation, Intratracheal - methods
Laryngeal Masks
Larynx - drug effects
Larynx - metabolism
Medical sciences
Piperidines - administration & dosage
Piperidines - pharmacokinetics
Propofol - administration & dosage
Propofol - pharmacokinetics
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Zusammenfassung:Propofol and remifentanil are the drugs of choice for insertion of the supraglottic airway without muscle relaxants for short duration surgery. In this study, we compared propofol concentrations required for insertion of laryngeal mask way (LMA) or laryngeal tube (LT) with and without remifentanil. We included children scheduled for surgeries lasting
ISSN:0003-2999
1526-7598
DOI:10.1213/01.ane.0000266447.23037.e4