[3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor

The cycloaddition of acetylenes with azides to give the corresponding 1,4-disubstituted 1,2,3-triazoles is reported using immobilised reagents and scavengers in pre-packed glass tubes in a modular flow reactor.

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Veröffentlicht in:Organic & biomolecular chemistry 2007-05, Vol.5 (10), p.1559-1561
Hauptverfasser: Smith, Christopher D, Baxendale, Ian R, Lanners, Steve, Hayward, John J, Smith, Stephen C, Ley, Steven V
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container_end_page 1561
container_issue 10
container_start_page 1559
container_title Organic & biomolecular chemistry
container_volume 5
creator Smith, Christopher D
Baxendale, Ian R
Lanners, Steve
Hayward, John J
Smith, Stephen C
Ley, Steven V
description The cycloaddition of acetylenes with azides to give the corresponding 1,4-disubstituted 1,2,3-triazoles is reported using immobilised reagents and scavengers in pre-packed glass tubes in a modular flow reactor.
doi_str_mv 10.1039/b702995k
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source MEDLINE; Royal Society of Chemistry Journals Archive (1841-2007); Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Alkynes - chemistry
Azides - chemistry
Catalysis
Chemistry, Pharmaceutical - instrumentation
Chemistry, Pharmaceutical - methods
Copper - chemistry
Equipment Design
Magnetic Resonance Spectroscopy
Models, Chemical
Peptides - chemistry
Triazoles - chemistry
title [3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor
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