[3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor

[3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor

The cycloaddition of acetylenes with azides to give the corresponding 1,4-disubstituted 1,2,3-triazoles is reported using immobilised reagents and scavengers in pre-packed glass tubes in a modular flow reactor.

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Veröffentlicht in:Organic & biomolecular chemistry 2007-05, Vol.5 (10), p.1559-1561
Hauptverfasser: Smith, Christopher D, Baxendale, Ian R, Lanners, Steve, Hayward, John J, Smith, Stephen C, Ley, Steven V
Format: Artikel
Sprache:eng
Schlagworte:
Alkynes - chemistry
Azides - chemistry
Catalysis
Chemistry, Pharmaceutical - instrumentation
Chemistry, Pharmaceutical - methods
Copper - chemistry
Equipment Design
Magnetic Resonance Spectroscopy
Models, Chemical
Peptides - chemistry
Triazoles - chemistry
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Zusammenfassung:The cycloaddition of acetylenes with azides to give the corresponding 1,4-disubstituted 1,2,3-triazoles is reported using immobilised reagents and scavengers in pre-packed glass tubes in a modular flow reactor.
ISSN:1477-0520
1477-0539
DOI:10.1039/b702995k