Effect of alkyl chain parity on the face-selective crystal growth of a drug polymorph

Effect of alkyl chain parity on the face-selective crystal growth of a drug polymorph

Carboxy terminated alkanethiol self-assembled monolayers promote the face-selective nucleation of the P-monoclinic polymorph of carbamazepine; the type of face nucleated depends on the parity of the alkyl chain.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2007-01 (24), p.2476-2478
Hauptverfasser: Dabros, Marta, Thalladi, Venkat R
Format: Artikel
Sprache:eng
Schlagworte:
Alkanes - chemistry
Anticonvulsants - chemistry
Carbamazepine - chemistry
Crystallization
Crystallography, X-Ray
Dimerization
Models, Chemical
Surface Properties
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Zusammenfassung:Carboxy terminated alkanethiol self-assembled monolayers promote the face-selective nucleation of the P-monoclinic polymorph of carbamazepine; the type of face nucleated depends on the parity of the alkyl chain.
ISSN:1359-7345
1364-548X
DOI:10.1039/b700222j