Outcomes of Kidneys from Donors After Cardiac Death: Implications for Allocation and Preservation

Although donation after cardiac death (DCD) kidneys have a high incidence of delayed graft function (DGF) and have been considered marginal, no tool for stratifying risk of graft loss nor a specific policy governing their allocation exist. We compared outcomes of 2562 DCD, 62 800 standard criteria d...

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Veröffentlicht in:	American journal of transplantation 2007-07, Vol.7 (7), p.1797-1807
Hauptverfasser:	Locke, J. E., Segev, D. L., Warren, D. S., Dominici, F., Simpkins, C. E., Montgomery, R. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allocation Biological and medical sciences Cohort Studies Death, Sudden, Cardiac donation after cardiac death Humans kidney transplantation Kidney Transplantation - statistics & numerical data Medical sciences Middle Aged Organ Preservation outcomes preservation Proportional Hazards Models Prospective Studies Regression Analysis Resource Allocation Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system Tissue Donors Treatment Outcome
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Beschreibung
Zusammenfassung:	Although donation after cardiac death (DCD) kidneys have a high incidence of delayed graft function (DGF) and have been considered marginal, no tool for stratifying risk of graft loss nor a specific policy governing their allocation exist. We compared outcomes of 2562 DCD, 62 800 standard criteria donor (SCD) and 12 812 expanded criteria donor (ECD) transplants reported between 1993 and 2005, and evaluated factors associated with risk of graft loss and DGF in DCD kidneys. Donor age was the only criterion used in the definition of ECD kidneys that independently predicted graft loss among DCD kidneys. Kidneys from DCD donors
ISSN:	1600-6135 1600-6143
DOI:	10.1111/j.1600-6143.2007.01852.x