Utility of lung density measurements in the diagnosis of emphysema

Summary Background The role of computerised tomography (CT) lung density measurements in objective quantification of emphysema is uncertain. The aim of this study was to determine normal reference values for CT lung density measurements and investigate their utility in identifying subjects with clin...

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Veröffentlicht in:	Respiratory medicine 2007-07, Vol.101 (7), p.1512-1520
Hauptverfasser:	Marsh, Suzanne, Aldington, Sarah, Williams, Mathew V, Nowitz, Michael R, Kingzett-Taylor, Andrew, Weatherall, Mark, Shirtcliffe, Philippa M, McNaughton, Amanda A, Pritchard, Alison, Beasley, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aging - physiology Algorithms Biological and medical sciences Chronic obstructive pulmonary disease, asthma Computerised tomography Emphysema Female Frequency distribution Humans Image Processing, Computer-Assisted - methods Lung - diagnostic imaging Lung density measurements Lung disease Lungs Male Medical imaging Medical sciences Methods Middle Aged Pneumology Pulmonary Emphysema - diagnostic imaging Pulmonary/Respiratory Reference Values Respiratory diseases Respiratory Function Tests Sex Characteristics Tomography, X-Ray Computed - methods
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Zusammenfassung:	Summary Background The role of computerised tomography (CT) lung density measurements in objective quantification of emphysema is uncertain. The aim of this study was to determine normal reference values for CT lung density measurements and investigate their utility in identifying subjects with clinical emphysema. Methods Normal subjects (non-smokers, no respiratory disease, n =185) and subjects with clinical emphysema (post-bronchodilator FEV1 /FVC
ISSN:	0954-6111 1532-3064
DOI:	10.1016/j.rmed.2007.01.002