Bicuspid Aortic Valve Morphology and Interventions in the Young

Bicuspid Aortic Valve Morphology and Interventions in the Young Susan M. Fernandes, Paul Khairy, Stephen P. Sanders, Steven D. Colan Bicuspid aortic valve (BAV) with right-noncoronary leaflet (R-N) fusion is associated with a greater degree of valve dysfunction compared with other subtypes, but the correlation with clinical outcomes is unknown. Our objective was to determine whether a morphologic subtype of BAV is associated with valve intervention in the young. We performed a nested cohort study of 310 patients with bicuspid aortic valve. The R-N fusion was associated with a more rapid progression of aortic stenosis and regurgitation and a greater incidence of valve intervention in the young.